Transforming medical devices for improved patient outcomes

Publications

Evolution of Drug-Eluting Stent Drug Elution Profile: Is A Crystalline Drug Form the Ideal Solution?

Giuseppe Sangiorgi, MD; Riccardo Colantonio, MD, PhD; Fabio De Luca, MD European Medical Journal Interventional Cardiology. June 2016; 4(1):55-67

Technical Overview On the MiStent Coronary Stent

James B. McClain, PhD; Wenda C. Carlyle, PhD; Dennis J. Donohoe, MD; John A. Ormiston, MB, ChB Minerva Cardioangiologica. in press. Epub ahead of print May 2016

Comparison of the Absorbable Polymer Sirolimus-Eluting Stent (MiStent) to the Durable Polymer Everolimus-Eluting Stent (Xience) (from the DESSOLVE I/II and ISAR-TEST-4 Studies)

Alexandra J. Lansky, M.D.; Adnan Kastrati, M.D.; Elazer R. Edelman, M.D., Ph.D.; Helen Parise, Sc.D.; Vivian G. Ng, M.D.; John Ormiston, M.D.; William Wijns, M.D.; and Robert A. Byrne, M.B., B.Ch., Ph.D. American Journal of Cardiology, February 15, 2016, Volume 117, Issue 4, pp 532-538.

Evaluation of a crystalline sirolimus-eluting coronary stent with a bioabsorbable polymer designed for rapid dissolution: two-year outcomes from the DESSOLVE I and II trials

William Wijns, M.D., Ph.D.; Maarten Jan Suttorp, M.D., Ph.D.; Leszek Zagozdzon, M.D.; Marie-Claude Morice, M.D.; Dougal McClean, M.D.; Pieter Stella, M.D.; Dennis Donohoe, M.D.; Charlene Knape, M.T.; John Ormiston, M.B.Ch.B. for the DESSOLVE I and DESSOLVE II Investigators EuroIntervention 2015 11-online publish-ahead-of-print September 2015

Bioabsorbable Polymer-Coated Sirolimus-Eluting Stent Implantation Preserves Coronary Vasomotion: A DESSOLVE II Trial Sub-study

Dan Rusinaru, M.D., Ph.D.; Mathias Vrolix, M.D.; Stefan Verheye, M.D.; Saqib Chowdhary, M.D., Ph.D.; Danny Schoors, M.D.; Carlo Di Mario, M.D., Ph.D.; Walter Desmet, M.D., Ph.D.; Dennis J. Donohoe, M.D.; John A. Ormiston, MB, ChB, Ph.D.; Charlene Knape, M.T.; Hiram Bezerra, M.D., Ph.D.; Alexandra Lansky, M.D.; and William Wijns, M.D., Ph.D. on behalf of the DESSOLVE II Investigators Catheterization and Cardiovascular Interventions 2015 86(7):1141-1150

Randomised Study of a Bioabsorbable Polymer-Coated Sirolimus-Eluting Stent: Results of the DESSOLVE II Trial

William Wijns, M.D., Ph.D.; Mathias Vrolix, M.D.; Stefan Verheye, M.D., Ph.D.; Danny Schoors, M.D., Ph.D.; Ton Slagboom, M.D.; Marcel Gosselink, M.D.; Edouard Benit, M.D.; Dennis Donohoe, M.D.; Charlene Knape, M.T.; Guilherme F. Attizzani, M.D.; Alexandra J. Lansky, M.D.; John Ormiston, M.D.; the DESSOLVE II Investigators EuroIntervention 2015 10(12):1383-1390

Serial Assessment by Optical Coherence Tomography of Early and Late Vascular Responses After Implantation of an Absorbable-Coating Sirolimus-Eluting Stent (from the First-in-Human DESSOLVE I Trial)

Guilherme F. Attizzani, M.D.; Hiram G. Bezerra, M.D., Ph.D.; John Ormiston, M.B.Ch.B.; Wei Wang, Ph.D.; Dennis Donohoe, M.D.; William Wijns, M.D., Ph.D.; Marco A. Costa, M.D., Ph.D.
The American Journal of Cardiology 2013 112(10):1557-1564

First-In-Human Evaluation of a Bioabsorbable Polymer-Coated Sirolimus-Eluting Stent Imaging and Clinical Results of the DESSOLVE I Trial 

John Ormiston, M.B.Ch.B.; Mark Webster, M.B.Ch.B.; James Stewart, M.B.Ch.B.; Mathias Vrolix, M.D.; Robert Whitbourn, M.B.B.S.; Dennis Donohoe, M.D.; Charlene Knape, M.T.; Alexandra Lansky, M.D.; Guilherme F. Attizzani, M.D.; Peter Fitzgerald, M.D., Ph.D.; David E. Kandzari, M.D.; William Wijns, M.D., Ph.D. Journal of American College of Cardiology: Cardiovascular Interventions 2013 6(10):1026-1034

Serial Evaluation of Vascular Response After Implantation of a New Sirolimus-Eluting Stent With Bioabsorbable Polymer (MISTENT®): An Optical Coherence Tomography and Histopathological Study

Guilherme F. Attizzani, M.D.; Hiram G. Bezerra, M.D., Ph.D.; Daniel Chamié, M.D.; Yusuke Fujino, M.D.; Anna-Maria Spognardi; James R.L. Stanley, M.S.D.V.M.; Hirosada Yamamoto, M.D., Emile Mehanna, M.D., Wei Wang, M.S.; Wenda C. Carlyle, Ph.D.; James B. McClain, Ph.D.; Marco A. Costa, M.D., Ph.D. Journal of Invasive Cardiology 2012; 24(11):560‐568

Enhanced Drug Delivery Capabilities from Stents Coated with Absorbable Polymer and Crystalline Drug

Wenda C. Carlyle, Ph.D.; James B. McClain, Ph.D.; Abraham R. Tzafriri, Ph.D.; Lynn Bailey; Brett G. Zani, Ph.D.; Peter M. Markham; James R.L. Stanley, M.S., D.V.M.; Elazer R. Edelman, M.D., Ph.D. Journal of Controlled Release 2012; 162(3):561-567